National Institutes of Health (NIH)
1 active project
Gender Identity Algorithm
Scientific Questions Being Studied
Previous investigations into the use of diagnosis codes for identifying non-binary gender identities used large databases like Kaiser Permanente or Medicare. However, these researchers did not have access to the gold standard where the patient’s self-reported gender identity is known. We aim to build an algorithm using socio-demographics, diagnosis, procedure, and medication codes from electronic health records that can identify transgender identity in large medical records datasets. Comparing this algorithmic method to the gold standard of self reported gender identity in All of Us will allow us to create a robust algorithm for application in datasets where self-reported gender identity is not collected. Additional strengths of this pilot project include building an algorithm in a dataset with patients across multiple health systems.
- Population Health
We propose to create an algorithm with diagnostic, procedure, and medication codes from electronic health records to identify transgender individuals using a gold standard for gender identity. Predictors of transgender status will be selected based on consultations with clinicians with expertise in transgender healthcare. These variables include sociodemographic (age, race/ethnicity), ICD-9/10 diagnosis codes (gender dysphoria), procedure codes for gender-affirming procedures (e.g. hysterectomy), and prescribed medications. We will use machine learning techniques to classify participants as transmen, transwomen or non-binary, including 400 transgender and 520 non-binary participants, in All of Us.
We anticipate that our findings will inform future identification measures of transgender and gender non-conforming/non binary individuals in electronic medical health record systems and/or large epidemiological datasets. This initial assessment will establish a basis for future work to identify health outcomes and risk factors within sexual gender minority populations.
Demographic Categories of Interest
- Gender Identity
- Jalen Brown - Other, National Institutes of Health (NIH)
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