Alireza Majd
Research Fellow, University of California, San Francisco
6 active projects
G2H_AllofUSs
Scientific Questions Being Studied
investigating the relationship between genetics, vaccinology and immunology, with an effort to describe the heterogeneity of immune response to measles vaccine among individuals from different genetic backgrounds.
Project Purpose(s)
- Disease Focused Research (measles)
- Ancestry
Scientific Approaches
investigate genetic variants that impact the response to the measles vaccine and testing the hypothesis that structural variants influence the generation of antibodies against the measles vaccine.
Anticipated Findings
This project will have a significant impact on the current state of the field by advancing our understanding of the genetic factors, i.e. both SNPs and SVs, influencing the response to the measles vaccine. Despite the vaccine's overall effectiveness, a considerable percentage of individuals fail to develop sufficient protective antibodies, leading to outbreaks and potential fatalities. By exploring the complex interplay between genetics and vaccine efficacy, this project aims to fill the existing knowledge gaps.
Demographic Categories of Interest
- Race / Ethnicity
Data Set Used
Controlled TierResearch Team
Owner:
- Oscar Rodriguez - Research Fellow, Baylor College of Medicine
- Luz Arroyo Cruz - Research Fellow, Universidad Central del Caribe
- Alireza Majd - Research Fellow, University of California, San Francisco
DGBIs_On_AllofUs
Scientific Questions Being Studied
Not applicable - this workspace is intended to be an starting point for developing a genome-wide association study pipeline on the All of Us genomic data studying Disorders of Gut-Brain Interactions.
Project Purpose(s)
- Educational
Scientific Approaches
Not applicable - This workspace is more exploration of data and testing the GWAS pipeline on AllofUs.
Anticipated Findings
Not applicable - outcome of this workspace would be educational purposes and also a specified GWAS pipeline for DGBIs.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Registered TierResearch Team
Owner:
- Alireza Majd - Research Fellow, University of California, San Francisco
- Ali Kalantari - Graduate Trainee, University of California, San Francisco
DGBIs_On_AllofUs
Scientific Questions Being Studied
Not applicable - this workspace is intended to be an starting point for developing a genome-wide association study pipeline on the All of Us genomic data studying Disorders of Gut-Brain Interactions.
Project Purpose(s)
- Ancestry
Scientific Approaches
Not applicable - This workspace is more exploration of data and testing the GWAS pipeline on AllofUs.
Anticipated Findings
Not applicable - outcome of this workspace would be educational purposes and also a specified GWAS pipeline for DGBIs.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Controlled TierResearch Team
Owner:
- Alireza Majd - Research Fellow, University of California, San Francisco
- Ali Kalantari - Graduate Trainee, University of California, San Francisco
Tutorial
Scientific Questions Being Studied
In this workshop, I am trying to get familiar with the gastrointestinal dataset at All of Us. In doing so I'll explore the distribution of the diseases across the US, and compare the relevance of these diseases amongst different ages and groups.
Project Purpose(s)
- Educational
Scientific Approaches
In this workshop, the scientific approach I am planning to use is to use descriptive statistics to get familiar with the distribution of the gastrointestinal dataset at All of Us. In doing so I'll explore the distribution of the diseases across the US, and compare the relevance of these diseases amongst different ages and groups.
Anticipated Findings
Anticipated findings from the study could show where these diseases are staggered in the nation and ultimately help motivate allocating resources to those areas.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Controlled TierResearch Team
Owner:
- Alireza Majd - Research Fellow, University of California, San Francisco
- Ali Kalantari - Graduate Trainee, University of California, San Francisco
Duplicate of Introductory example of GWAS with type 2 diabetes phenotype
Scientific Questions Being Studied
Not applicable - this workspace is intended to be an introductory example of how to do a genome-wide association study on the All of Us genomic data that individuals can easily click through and understand.
Project Purpose(s)
- Educational
Scientific Approaches
Not applicable - this workspace is intended to be an introductory example of how to do a genome-wide association study on the All of Us genomic data that individuals can easily click through and understand.
Anticipated Findings
Not applicable - this workspace is intended to be an introductory example of how to do a genome-wide association study on the All of Us genomic data that individuals can easily click through and understand.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Controlled TierDup of Studies of Autosomal Dominant Polycystic Kidney Disease
Scientific Questions Being Studied
Not applicable - this workspace is intended to be an example of how use the Researcher Workbench by studying participants with Autosomal Polycystic Kidney Disease (ADPKD)
Project Purpose(s)
- Educational
Scientific Approaches
Not applicable - this workspace is intended to be an example of how use the Researcher Workbench by studying participants with Autosomal Polycystic Kidney Disease (ADPKD)
Anticipated Findings
Not applicable - this workspace is intended to be an example of how use the Researcher Workbench by studying participants with Autosomal Polycystic Kidney Disease (ADPKD)
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Registered TierRequest a Review of this Research Project
You can request that the All of Us Resource Access Board (RAB) review a research purpose description if you have concerns that this research project may stigmatize All of Us participants or violate the Data User Code of Conduct in some other way. To request a review, you must fill in a form, which you can access by selecting ‘request a review’ below.
