Graduate Trainee, Mass General Brigham
1 active project
Functional GI Disorders Among Black/AA Patients
Scientific Questions Being Studied
The aim of this study is to explore and characterize common functional GI diseases among patients who identify as African American or Black. We are interested specifically in irritable bowel syndrome (IBS). As a part of this research study, we will be comparing comorbidities, demographic, socioeconomic information, and medical management among among patients who identify as African American or Black, as well as Caucasians. Minority populations are more likely to face health disparities and issues related to access to care, however they are frequently underrepresented in clinical research. Research focused on investigating diseases which affect people from a an array of racial and ethnic backgrounds is one way to help take steps towards ensuring quality of clinical care for all patients.
- Disease Focused Research (Functional GI Diseases)
To complete this study, we plan to utilize several datasets, based primarily on four different cohort populations from the All of Us database, including a cohort of Black patients with IBS, a cohort of Black patients without IBS, a cohort of White patients with IBS, and one without. By creating an age and sex matched control group, we will not only be able to compare differences in overall health status, but also differences in patient socioeconomic status, perceptions of the health care which they receive based on survey data, as well as basic demographics. Following the creation of the cohorts, we will use the exported data, All of US notebook and statistical software to identify whether or not there are meaningful differences between the groups.
There have not been many studies of functional GI diseases, or IBS in general which have been specifically focused on Black populations, however one epidemiological study from 2005 demonstrated that IBS occurs less frequently among African Americans, although the disease IBS affects quality of life among both ethnicities, the degree of impairment is similar. A second population-based study has been published which explored racial differences in the overlap between IBS and dyspepsia between African American and Caucasians. Comorbid functional GI disorders other than dyspepsia have not been explored. Specific perceptions of care have also not been thoroughly explored in this population. Our study utilizing All of Us Data will contribute to the field by creating a more holistic picture of the characteristics, medical management and health perspectives of black patients living with IBS, using a generalizable population database.
Demographic Categories of Interest
- Race / Ethnicity
- Sex at Birth
- Gender Identity
Data Set UsedRegistered Tier
- Taylor Boyd - Graduate Trainee, Mass General Brigham
- Casey Silvernale - Graduate Trainee, Mass General Brigham
- Kyle Staller - Early Career Tenure-track Researcher, Mass General Brigham
You can request that the All of Us Resource Access Board (RAB) review a research purpose description if you have concerns that this research project may stigmatize All of Us participants or violate the Data User Code of Conduct in some other way. To request a review, you must fill in a form, which you can access by selecting ‘request a review’ below.