Jonathan Sanchez
Graduate Trainee, George Mason University
2 active projects
Colorectal Cancer Causal Analysis
Scientific Questions Being Studied
We will study the causation of colorectal cancer
Project Purpose(s)
- Disease Focused Research (colorectal cancer)
- Population Health
- Social / Behavioral
- Drug Development
Scientific Approaches
We will use Lasso regression and temporal analysis to study causation of the disease.
Anticipated Findings
We anticipate to find the temporal order of events leading to cancer diagnosis as well as describe the relation of these factors with each other.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Registered TierResearch Team
Owner:
- Jonathan Sanchez - Graduate Trainee, George Mason University
- CHANDANA DASARRAJU - Graduate Trainee, George Mason University
- Aarif Chittoor Mohammed - Graduate Trainee, George Mason University
Colorectal Cancer Predictive Model
Scientific Questions Being Studied
What is the effectiveness of colorectal cancer screening in predicting the incidence of colorectal cancer in a diverse population in the United States, and how does the temporal sequence of events and clusters of conditions affect the causal relationship between screening and cancer incidence? According to the American Cancer Society, the current 5-year survival rate for localized colorectal cancer is around 90%, but this decreases to 14% for individuals with distant metastases. This highlights the importance of early detection through screening, as it can lead to more favorable treatment outcomes and significantly improve the chances of survival.
Project Purpose(s)
- Disease Focused Research (colorectal cancer)
- Population Health
- Social / Behavioral
- Drug Development
Scientific Approaches
We will use temporal analysis based on LASSO Regression and will create a network of the events leading to colorectal cancer using Netica.
Anticipated Findings
The findings of this study will promote knowledge on the sequence of events for colorectal cancer diagnosis as well as causal association between variables leading up to the diagnosis.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Registered TierRequest a Review of this Research Project
You can request that the All of Us Resource Access Board (RAB) review a research purpose description if you have concerns that this research project may stigmatize All of Us participants or violate the Data User Code of Conduct in some other way. To request a review, you must fill in a form, which you can access by selecting ‘request a review’ below.
