Sophia Wang

Early Career Tenure-track Researcher, Stanford University

3 active projects

15month Version Two ophthalmology epidemiology(DV3)

We would like to evaluate the epidemiology, treatments, and health outcomes of eye diseases using the diverse population in the All Of Us project. Over 12 million people in the United States over the age of 40 have visual impairment,…

Scientific Questions Being Studied

We would like to evaluate the epidemiology, treatments, and health outcomes of eye diseases using the diverse population in the All Of Us project. Over 12 million people in the United States over the age of 40 have visual impairment, and over 3 million have visual impairment despite glasses, contacts, or other treatments. Visual impairment has severe impacts on patients' quality of life and mortality. There are many common causes of visual impairment, including some reversible (such as cataract) and others that are treatable but can still cause irreversible vision loss (macular degeneration, glaucoma, diabetic retinopathy). Some of these diseases disproportionately impact minority populations (e.g. glaucoma in African Americans and Hispanics).
We hope to broadly characterize the prevalence of eye diseases in this cohort, as well as associated medical and surgical treatments. We hope to be able to investigate risk factors, patterns and outcomes of treatment of different eye diseases.

Project Purpose(s)

  • Disease Focused Research (eye diseases)
  • Population Health

Scientific Approaches

We plan to primarily use the EHR, survey, and physical measurements dataset to describe the epidemiology of eye diseases, using encounter-level billing codes to determine their presence or absence. We plan to investigate risk factors for these eye diseases, including demographics, medications, physical measurements (to the extent available), survey data, and other associated diagnoses. We will begin with simple descriptive statistics. In diagnoses with sufficiently sized cohort, we will also build logistic regressions to evaluate risk factors for diagnosis.
We will also evaluate treatment patterns (medical and surgical) for different eye diseases, using EHR data of medications and surgeries undergone. We will characterize demographic and patterns in patterns of medications and surgeries.

Anticipated Findings

We anticipate that our findings will contribute broadly to the knowledge of epidemiology of eye diseases in the US, as well as improve our understanding of patterns of treatments and outcomes of eye diseases in the US. In this diverse population, we will also be able to see if there are disparities in eye diseases and their treatment patterns and outcomes.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Research Team

Owner:

  • Wendeng Hu - Project Personnel, Stanford University
  • Sophia Wang - Early Career Tenure-track Researcher, Stanford University

Version Two ophthalmology epidemiology(DV3)

We would like to evaluate the epidemiology, treatments, and health outcomes of eye diseases using the diverse population in the All Of Us project. Over 12 million people in the United States over the age of 40 have visual impairment,…

Scientific Questions Being Studied

We would like to evaluate the epidemiology, treatments, and health outcomes of eye diseases using the diverse population in the All Of Us project. Over 12 million people in the United States over the age of 40 have visual impairment, and over 3 million have visual impairment despite glasses, contacts, or other treatments. Visual impairment has severe impacts on patients' quality of life and mortality. There are many common causes of visual impairment, including some reversible (such as cataract) and others that are treatable but can still cause irreversible vision loss (macular degeneration, glaucoma, diabetic retinopathy). Some of these diseases disproportionately impact minority populations (e.g. glaucoma in African Americans and Hispanics).
We hope to broadly characterize the prevalence of eye diseases in this cohort, as well as associated medical and surgical treatments. We hope to be able to investigate risk factors, patterns and outcomes of treatment of different eye diseases.

Project Purpose(s)

  • Disease Focused Research (eye diseases)
  • Population Health

Scientific Approaches

We plan to primarily use the EHR, survey, and physical measurements dataset to describe the epidemiology of eye diseases, using encounter-level billing codes to determine their presence or absence. We plan to investigate risk factors for these eye diseases, including demographics, medications, physical measurements (to the extent available), survey data, and other associated diagnoses. We will begin with simple descriptive statistics. In diagnoses with sufficiently sized cohort, we will also build logistic regressions to evaluate risk factors for diagnosis.
We will also evaluate treatment patterns (medical and surgical) for different eye diseases, using EHR data of medications and surgeries undergone. We will characterize demographic and patterns in patterns of medications and surgeries.

Anticipated Findings

We anticipate that our findings will contribute broadly to the knowledge of epidemiology of eye diseases in the US, as well as improve our understanding of patterns of treatments and outcomes of eye diseases in the US. In this diverse population, we will also be able to see if there are disparities in eye diseases and their treatment patterns and outcomes.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Research Team

Owner:

  • Wendeng Hu - Project Personnel, Stanford University
  • Sophia Wang - Early Career Tenure-track Researcher, Stanford University
  • Eric Lee - Graduate Trainee, Stanford University

ophthalmology epidemiology

We would like to evaluate the epidemiology, treatments, and health outcomes of eye diseases using the diverse population in the All Of Us project. Over 12 million people in the United States over the age of 40 have visual impairment,…

Scientific Questions Being Studied

We would like to evaluate the epidemiology, treatments, and health outcomes of eye diseases using the diverse population in the All Of Us project. Over 12 million people in the United States over the age of 40 have visual impairment, and over 3 million have visual impairment despite glasses, contacts, or other treatments. Visual impairment has severe impacts on patients' quality of life and mortality. There are many common causes of visual impairment, including some reversible (such as cataract) and others that are treatable but can still cause irreversible vision loss (macular degeneration, glaucoma, diabetic retinopathy). Some of these diseases disproportionately impact minority populations (e.g. glaucoma in African Americans and Hispanics).
We hope to broadly characterize the prevalence of eye diseases in this cohort, as well as associated medical and surgical treatments. We hope to be able to investigate risk factors, patterns and outcomes of treatment of different eye diseases.

Project Purpose(s)

  • Disease Focused Research (eye diseases)
  • Population Health

Scientific Approaches

We plan to primarily use the EHR, survey, and physical measurements dataset to describe the epidemiology of eye diseases, using encounter-level billing codes to determine their presence or absence. We plan to investigate risk factors for these eye diseases, including demographics, medications, physical measurements (to the extent available), survey data, and other associated diagnoses. We will begin with simple descriptive statistics. In diagnoses with sufficiently sized cohort, we will also build logistic regressions to evaluate risk factors for diagnosis.
We will also evaluate treatment patterns (medical and surgical) for different eye diseases, using EHR data of medications and surgeries undergone. We will characterize demographic and patterns in patterns of medications and surgeries.

Anticipated Findings

We anticipate that our findings will contribute broadly to the knowledge of epidemiology of eye diseases in the US, as well as improve our understanding of patterns of treatments and outcomes of eye diseases in the US. In this diverse population, we will also be able to see if there are disparities in eye diseases and their treatment patterns and outcomes.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Research Team

Owner:

  • Wendeng Hu - Project Personnel, Stanford University
  • Sophia Wang - Early Career Tenure-track Researcher, Stanford University
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