Undergraduate Student, University of Central Florida
1 active project
Ethnicity Disparities in Acute Myocardial Infarction in PLWH
Scientific Questions Being Studied
Research Question: This moderation analysis study will denote the influence of a third variable, Ethnicity (Moderator), on the relationship between CD4+ cell count (predictor 1) and viral load (predictor 2) and AMI (the outcome). The data needed for the statistical interpretation will be collected from the NIH-sponsored All of Us database.
CVD in the US is a significant threat, holding the title as the number one killer in America, disproportionately affecting minority communities. PLWH are more drastically affected by the implications of CVD and are at a significantly higher risk. Although a causal relationship exists between low CD4 cell count and AMI, the potential moderation effect of ethnicity has not been studied in this population.
- Population Health
Study participants will be 18 years of age or older and have a diagnosis of HIV infection. The following variables will be extracted for all study participants, as these pertain to the research hypotheses:
• Hispanic ethnicity (moderator)
• Most recent CD4 count (predictor)
• Most recent viral load (predictor)
• History of acute myocardial infarction (outcome)
Additionally, demographic variables (i.e., Race, Sex at birth, Gender identity, Birthplace, Annual income, Health insurance) will be extracted to ensure comparability among study groups.
We hypothesize that:
1. There is a strong association between the predictors (CD4 count and viral load) and AMI outcomes.
2. Hispanic ethnicity this expected association, we anticipate a higher OR for Hispanic PLWH.
Demographic Categories of Interest
- Race / Ethnicity
Data Set UsedRegistered Tier
You can request that the All of Us Resource Access Board (RAB) review a research purpose description if you have concerns that this research project may stigmatize All of Us participants or violate the Data User Code of Conduct in some other way. To request a review, you must fill in a form, which you can access by selecting ‘request a review’ below.