Vincent Lam

Research Fellow, National Institutes of Health (NIH)

1 active project

Reproducing the results of a UK Biobank study on Type 2 Diabetes

The study I am trying to replicate attempted to determine whether genetic ancestry and socioeconomic deprivation (SED) interact to affect one's risk of developing type 2 diabetes and whether this interaction varies depending on genetic ancestry type. Such insight may…

Scientific Questions Being Studied

The study I am trying to replicate attempted to determine whether genetic ancestry and socioeconomic deprivation (SED) interact to affect one's risk of developing type 2 diabetes and whether this interaction varies depending on genetic ancestry type. Such insight may help inform future health interventions.

Project Purpose(s)

  • Other Purpose (I am a research trainee trying to familiarize myself with both the All of Us workspace and working with All of Us data. To accomplish this, I will be attempting to replicate the results of a study conducted by my lab, which was published as an article titled "Socioeconomic deprivation and genetic ancestry interact to modify type 2 diabetes ethnic disparities in the United Kingdom". )

Scientific Approaches

Case / control cohorts will be made with individuals with type 2 diabetes and those without the disease, respectively. Analyses with be done in Python and R.

Anticipated Findings

The results are expected to those of the study I am attempting to replicate - socioeconomic deprivation is expected to increase the likelihood of developing type 2 diabetes among all demographic groups, but this effect is expected to be especially pronounced in individuals of African and Asian ancestry.

Demographic Categories of Interest

  • Race / Ethnicity
  • Access to Care
  • Education Level
  • Income Level

Data Set Used

Controlled Tier

Research Team

Owner:

  • Vincent Lam - Research Fellow, National Institutes of Health (NIH)

Collaborators:

  • Shivam Sharma - Graduate Trainee, Georgia Institute of Technology
  • Leonardo Marino-Ramirez - Senior Researcher, National Institutes of Health (NIH)
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