Lekha Pandya

Research Fellow, Washington University in St. Louis

4 active projects

PRS 2024

We intend to study the genomics of cardiovascular disease and the relationship to clinical and sociodemographic variables.

Scientific Questions Being Studied

We intend to study the genomics of cardiovascular disease and the relationship to clinical and sociodemographic variables.

Project Purpose(s)

  • Disease Focused Research (Cardiovascular disease)
  • Population Health
  • Ancestry

Scientific Approaches

We will utilize multimodal data from All of Us, including whole-sequencing data, EHR data, and survey data.

Anticipated Findings

We anticipate better characterization of the genomics of cardiovascular disease, thus enabling further therapeutic development in the field.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Data Set Used

Controlled Tier

Research Team

Owner:

  • Lekha Pandya - Research Fellow, Washington University in St. Louis

PRS modeling

Purpose of workspace is to explore All of Us genomic data and evaluate if appropriate for potential analyses of genetic risk in cardiovascular disease.

Scientific Questions Being Studied

Purpose of workspace is to explore All of Us genomic data and evaluate if appropriate for potential analyses of genetic risk in cardiovascular disease.

Project Purpose(s)

  • Disease Focused Research (arteriosclerotic cardiovascular disease)
  • Ancestry

Scientific Approaches

Population of interest is all patients with complete WGS data. Still undecided what methods and tools will be used, as dependent on results of preliminary data exploration.

Anticipated Findings

May contribute to more informed and personalized approaches to cardiovascular disease prevention.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Data Set Used

Controlled Tier

Research Team

Owner:

  • Lekha Pandya - Research Fellow, Washington University in St. Louis

Collaborators:

  • Nicolas Ledru - Graduate Trainee, Washington University in St. Louis

AoU Support Testing

Purpose of workspace is to explore All of Us genomic data and evaluate if appropriate for potential analyses of genetic risk in cardiovascular disease.

Scientific Questions Being Studied

Purpose of workspace is to explore All of Us genomic data and evaluate if appropriate for potential analyses of genetic risk in cardiovascular disease.

Project Purpose(s)

  • Ancestry

Scientific Approaches

Population of interest is all patients with complete WGS data. Still undecided what methods and tools will be used, as dependent on results of preliminary data exploration.

Anticipated Findings

May contribute to more informed and personalized approaches to cardiovascular disease prevention.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Data Set Used

Controlled Tier

Research Team

Owner:

  • Lekha Pandya - Research Fellow, Washington University in St. Louis

PRS modeling v7

Purpose of workspace is to explore All of Us genomic data and evaluate if appropriate for potential analyses of genetic risk in cardiovascular disease.

Scientific Questions Being Studied

Purpose of workspace is to explore All of Us genomic data and evaluate if appropriate for potential analyses of genetic risk in cardiovascular disease.

Project Purpose(s)

  • Disease Focused Research (arteriosclerotic cardiovascular disease)
  • Ancestry

Scientific Approaches

Population of interest is all patients with complete WGS data. Still undecided what methods and tools will be used, as dependent on results of preliminary data exploration.

Anticipated Findings

May contribute to more informed and personalized approaches to cardiovascular disease prevention.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Data Set Used

Controlled Tier

Research Team

Owner:

  • Lekha Pandya - Research Fellow, Washington University in St. Louis
1 - 4 of 4
<
>
Request a Review of this Research Project

You can request that the All of Us Resource Access Board (RAB) review a research purpose description if you have concerns that this research project may stigmatize All of Us participants or violate the Data User Code of Conduct in some other way. To request a review, you must fill in a form, which you can access by selecting ‘request a review’ below.