Javan Carter
Research Associate, All of Us Researcher Academy/RTI International
9 active projects
AoU Researcher Academy – Fitbit Use Case Workshop
Scientific Questions Being Studied
We will be conducting a workshop for the All of Us Researcher Academy to help potential researchers familiarize themselves with the Researcher Workbench and the wearables data available in the platform. As a use case demonstration, we will be exploring two scientific questions: 1) Is the cohort of Fitbit users in the AoU database representative of the rest of the AoU population? The general U.S. population? And 2) What is the association between the Social Determinants of Health and Heart Rate?
Project Purpose(s)
- Educational
Scientific Approaches
We will use Fitbit data and survey data to explore these questions. We will clean the data, merge the two data types, and generate descriptive statistics.
Anticipated Findings
Our goal for researchers attending our workshop is to equip them to be able to use what they learn about AoU wearables data during this workshop to answer their own research questions.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Registered TierResearch Team
Owner:
- Margaret Moakley - Project Personnel, All of Us Researcher Academy/RTI International
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
- Carlos Macuada - Project Personnel, All of Us Researcher Academy/RTI International
Collaborators:
- Stefanie Boyles - Graduate Trainee, University of Arizona
- Subhosit Ray - Research Fellow, Florida Atlantic University
- Mariana Sanchez - Mid-career Tenured Researcher, Florida International University
- Gira Ravelo - Research Associate, Florida International University
- Denise Dawson - Graduate Trainee, University of North Carolina, Greensboro
RTI Researcher Academy Coach Training Workspace-Registered
Scientific Questions Being Studied
This is a training workbench designed to help Institutional Champions with research and educational needs.
Project Purpose(s)
- Educational
Scientific Approaches
This is a training workbench designed to help Institutional Champions with research and educational needs.
Anticipated Findings
This is a training workbench designed to help Institutional Champions with research and educational needs.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Registered TierResearch Team
Owner:
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
Collaborators:
- Stefanee Tillman - Project Personnel, All of Us Researcher Academy/RTI International
RTI Researcher Academy Coach Training Workbench
Scientific Questions Being Studied
This is a training workbench designed to help Institutional Champions with research and educational needs.
Project Purpose(s)
- Educational
Scientific Approaches
This is a training workbench designed to help Institutional Champions with research and educational needs.
Anticipated Findings
This is a training workbench designed to help Institutional Champions with research and educational needs.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Controlled TierResearch Team
Owner:
- Stefanee Tillman - Project Personnel, All of Us Researcher Academy/RTI International
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
Collaborators:
- Vincenzo Malo - Project Personnel, All of Us Researcher Academy/RTI International
- Trey-Rashad Hawkins - Project Personnel, All of Us Researcher Academy/RTI International
- Kristin Glaze - Project Personnel, All of Us Researcher Academy/RTI International
- Barrett Montgomery - Early Career Tenure-track Researcher, All of Us Researcher Academy/RTI International
RTI Research Academy R workshop (sickle cell project) with v.8
Scientific Questions Being Studied
This workbench is designed to be used as an educational tool for the RTI Research academy. Therefore, there isn't a scientific question that will be explored. The pseudo- question is associated with Sickle cell and how to identify it using GWAS. The target audience are students, graduate students, post-docs, and PIs from HBCUs (Historically Black Community Colleges/ Universities). The goal is the reduce the gap of knowledge between HBCUs and PWI and give HBCUs the tools and confidence to use the AoU workbench.
Project Purpose(s)
- Educational
Scientific Approaches
We will be creating a cohort of individuals with the sickle cell disease and those who do not (control). This cohort will be converted into a dataset and processed in the R notebook. We will be using PLINK as a genotyping and GWAS tool. The overall goal is "education without intimidation". We want to introduce these topics to our students in the most parsimonious way with high accuracy and correctness to remove the fluff and allow the student to feel comfortable with the knowledge presented.
Anticipated Findings
There are no anticipated findings because of the nature of the project. This study will ultimately contribute to the scientific knowledge by advancing the knowledge of the individuals who take the course and eventually start their own amazing research study.
Demographic Categories of Interest
- Race / Ethnicity
Data Set Used
Controlled TierResearch Team
Owner:
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
Collaborators:
- Kristin Glaze - Project Personnel, All of Us Researcher Academy/RTI International
DUPLICATE: RTI Research Academy R Workshop (Sickle Cell Project)
Scientific Questions Being Studied
This workbench is designed to be used as an educational tool for the RTI Research academy. Therefore, there isn't a scientific question that will be explored. The pseudo- question is associated with Sickle cell and how to identify it using GWAS. The target audience are students, graduate students, post-docs, and PIs from HBCUs (Historically Black Community Colleges/ Universities). The goal is the reduce the gap of knowledge between HBCUs and PWI and give HBCUs the tools and confidence to use the AoU workbench.
Project Purpose(s)
- Educational
Scientific Approaches
We will be creating a cohort of individuals with the sickle cell disease and those who do not (control). This cohort will be converted into a dataset and processed in the R notebook. We will be using PLINK as a genotyping and GWAS tool. The overall goal is "education without intimidation". We want to introduce these topics to our students in the most parsimonious way with high accuracy and correctness to remove the fluff and allow the student to feel comfortable with the knowledge presented.
Anticipated Findings
There are no anticipated findings because of the nature of the project. This study will ultimately contribute to the scientific knowledge by advancing the knowledge of the individuals who take the course and eventually start their own amazing research study.
Demographic Categories of Interest
- Race / Ethnicity
Data Set Used
Controlled TierResearch Team
Owner:
- Vincenzo Malo - Project Personnel, All of Us Researcher Academy/RTI International
- Trey-Rashad Hawkins - Project Personnel, All of Us Researcher Academy/RTI International
- Stefanee Tillman - Project Personnel, All of Us Researcher Academy/RTI International
- Kristin Glaze - Project Personnel, All of Us Researcher Academy/RTI International
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
RTI Type I Diabetes PRS Validation Analysis
Scientific Questions Being Studied
Based on the research done from the Sharp et. al. 2019 paper and the Qu et. al. paper, Polygenic Risk Scores (PRS's) were developed for European and African biological and ancestral groups. We would like to go and validate the PRS's against and independent cohort of individuals associated with Type I Diabetes to recalculate the PRS threshold using the all of us database. Additionally, we want to further validate the PRS's against other biological ancestral races such as East Asian and Hispanic.
Project Purpose(s)
- Disease Focused Research (type 1 diabetes mellitus)
- Methods Development
- Control Set
- Ancestry
Scientific Approaches
Create cohorts representing individuals with Type I Diabetes from various backgrounds and races based off of PTA ancestral predictions and run a customized PRS calculation script on the candidate PRS markers described in Qu et. al., 2022.
Anticipated Findings
The anticipated findings for the study could either be confirming that all 72 PRS candidate markers are sufficient across multiple ancestral populations, or that confoundment plays a role in the overall effect size of the PRS markers for given or specific ancestral populations, thus requiring new thresholds to be established for different ancestral populations, other than European.
Demographic Categories of Interest
- Race / Ethnicity
Data Set Used
Controlled TierResearch Team
Owner:
- Kristin Glaze - Project Personnel, All of Us Researcher Academy/RTI International
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
RTI OUD GWAS analysis
Scientific Questions Being Studied
The purpose of this workspace is to further explore the GWS significant loci identified in GWAS analyses of OUD using a more diverse and bigger sample.
Project Purpose(s)
- Ancestry
Scientific Approaches
The datasets will include cohorts of different combinations of parameters from All of Us, including their genomic data. The methods and tools will include QC and model selection for analyses using the notebooks.
Anticipated Findings
The anticipated findings from this study include further identification of novel loci associated with OUD given a more diverse dataset and confirmation of previous findings.
Demographic Categories of Interest
- Sex at Birth
- Gender Identity
- Sexual Orientation
Data Set Used
Controlled TierResearch Team
Owner:
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
Collaborators:
- Amy Moore - Research Associate, All of Us Researcher Academy/RTI International
P50 Opioid Meta Analysis
Scientific Questions Being Studied
This study intends to investigate the association between calcium and muscular weakness in an attempt to identify the role of calcium in muscle contraction.
Project Purpose(s)
- Educational
Scientific Approaches
This study will investigate actionable biological drives of opioid use disorder through completing a GWAS study.
Anticipated Findings
This is integral in contributing in the knowledge base regarding the biology underlying opioid use disorder.
Demographic Categories of Interest
- Race / Ethnicity
Data Set Used
Controlled TierResearch Team
Owner:
- Rahma Jamac - Other, All of Us Researcher Academy/RTI International
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
- Wendy Deng - Project Personnel, All of Us Researcher Academy/RTI International
- Caryn Willis - Research Associate, All of Us Researcher Academy/RTI International
RTI Research Academy R workshop (sickle cell project)
Scientific Questions Being Studied
This workbench is designed to be used as an educational tool for the RTI Research academy. Therefore, there isn't a scientific question that will be explored. The pseudo- question is associated with Sickle cell and how to identify it using GWAS. The target audience are students, graduate students, post-docs, and PIs from HBCUs (Historically Black Community Colleges/ Universities). The goal is the reduce the gap of knowledge between HBCUs and PWI and give HBCUs the tools and confidence to use the AoU workbench.
Project Purpose(s)
- Educational
Scientific Approaches
We will be creating a cohort of individuals with the sickle cell disease and those who do not (control). This cohort will be converted into a dataset and processed in the R notebook. We will be using PLINK as a genotyping and GWAS tool. The overall goal is "education without intimidation". We want to introduce these topics to our students in the most parsimonious way with high accuracy and correctness to remove the fluff and allow the student to feel comfortable with the knowledge presented.
Anticipated Findings
There are no anticipated findings because of the nature of the project. This study will ultimately contribute to the scientific knowledge by advancing the knowledge of the individuals who take the course and eventually start their own amazing research study.
Demographic Categories of Interest
- Race / Ethnicity
Data Set Used
Controlled TierResearch Team
Owner:
- Javan Carter - Research Associate, All of Us Researcher Academy/RTI International
Collaborators:
- Trey-Rashad Hawkins - Project Personnel, All of Us Researcher Academy/RTI International
- Danielle Johnson - Project Personnel, All of Us Researcher Academy/RTI International
Request a Review of this Research Project
You can request that the All of Us Resource Access Board (RAB) review a research purpose description if you have concerns that this research project may stigmatize All of Us participants or violate the Data User Code of Conduct in some other way. To request a review, you must fill in a form, which you can access by selecting ‘request a review’ below.
