Anav Babbar
National Institutes of Health (NIH)
1 active project
Hypothyroidism genomics
Scientific Questions Being Studied
In previous work, certain genetic variants were found to be associated with hypothyroidism using techniques such as GWAS and PheWAS. Current work will leverage the diversity of the All of Us data to replicate and confirm the association between those variants and hypothyroidism, and possibly identify new variants that are associated with hypothyroidism.
Project Purpose(s)
- Disease Focused Research (hypothyroidism)
- Ancestry
Scientific Approaches
Will use All of Us genetic data and genomic techniques such as GWAS/PheWAS to identify genomic variants that are associated with hypothyroidism. Tools used include Python, R, Hail, SQL, etc.
Anticipated Findings
We seek to replicate and confirm previously identified variants associated with hypothyroidism, while possibly identifying new variants that could become targets of further study to understand the disease process of hypothyroidism. The diversity of the All of Us dataset may allow us to find these new variants.
Demographic Categories of Interest
This study will not center on underrepresented populations.
Data Set Used
Controlled Tier
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