Jinyoung Byun

Baylor College of Medicine

3 active projects

Lung Cancer GWAS

The aim in the proposed work is to characterize the genetic contributions to lung cancer development across different histological subtypes in multiple populations.

Scientific Questions Being Studied

The aim in the proposed work is to characterize the genetic contributions to lung cancer development across different histological subtypes in multiple populations.

Project Purpose(s)

  • Disease Focused Research (lung cancer)
  • Ancestry

Scientific Approaches

I would like to obtain GWAS data (case-control study) of the following:
1. lung cancer data
2. lung adenocarcinoma
3. lung squamous cell carcinoma
4. lung small cell carcinoma.

I will implement association tests to identify genetic variants influencing directly lung cancer risk and genetic epistasis analysis to develop the genetic interaction models in using plink and R.

Anticipated Findings

The expected findings from study can demonstrate the shared and distant genetic architectures across histology-specific and ancestry-specific subsets.

Demographic Categories of Interest

  • Race / Ethnicity
  • Sex at Birth
  • Geography

Data Set Used

Controlled Tier

Research Team

Owner:

DUPLICATE:Introductory example of GWAS with type 2 diabetes phenotype

Not applicable - this workspace is intended to be an introductory example of how to do a genome-wide association study on the All of Us genomic data that individuals can easily click through and understand.

Scientific Questions Being Studied

Not applicable - this workspace is intended to be an introductory example of how to do a genome-wide association study on the All of Us genomic data that individuals can easily click through and understand.

Project Purpose(s)

  • Educational

Scientific Approaches

Not applicable - this workspace is intended to be an introductory example of how to do a genome-wide association study on the All of Us genomic data that individuals can easily click through and understand.

Anticipated Findings

Not applicable - this workspace is intended to be an introductory example of how to do a genome-wide association study on the All of Us genomic data that individuals can easily click through and understand.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Data Set Used

Controlled Tier

Research Team

Owner:

DUPLICATE:How to Work with All of Us Genomic Data (Hail - Plink)(v6)

Not applicable - these notebooks demonstrate example analysis how to use Hail and PLINK to perform genome-wide association studies using the All of Us genomic data and phenotypic data.

Scientific Questions Being Studied

Not applicable - these notebooks demonstrate example analysis how to use Hail and PLINK to perform genome-wide association studies using the All of Us genomic data and phenotypic data.

Project Purpose(s)

  • Other Purpose (Demonstrate to the All of Us Researcher Workbench users how to get started with the All of Us genomic data and tools. It includes an overview of all the All of Us genomic data and shows some simple examples on how to use these data.)

Scientific Approaches

Not applicable - these notebooks demonstrate example analysis how to use Hail and PLINK to perform genome-wide association studies using the All of Us genomic data and phenotypic data.

Anticipated Findings

Not applicable - these notebooks demonstrate example analysis how to use Hail and PLINK to perform genome-wide association studies using the All of Us genomic data and phenotypic data.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Data Set Used

Controlled Tier

Research Team

Owner:

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