Evan Brittain

Mid-career Tenured Researcher, Vanderbilt University Medical Center

1 active project

Wearables Data and the Human Phenome

Our primary goal is to understand the interaction between activity levels and sleep quality with the development and progression of human disease. Higher physical activity is associated with lower prevalence and better outcomes in virtually every human disease. These analyses…

Scientific Questions Being Studied

Our primary goal is to understand the interaction between activity levels and sleep quality with the development and progression of human disease. Higher physical activity is associated with lower prevalence and better outcomes in virtually every human disease. These analyses will generate hypotheses guiding clinical and research interventions focused on activity and sleep to reduce morbidity and mortality in patients seeking care.

Project Purpose(s)

  • Population Health
  • Social / Behavioral

Scientific Approaches

We will examine the relationship between daily activity (steps, activity intensity) over time and the prevalence and progression of coded human diseases. We will use the Fitbit data, EHR-curated diagnoses, laboratory values, quality of life survey results, and clinical outcomes (hospitalizations/mortality).

Anticipated Findings

We expect to find that lower levels of activity are associated with a higher prevalence and more rapid progression of chronic diseases. These data will provide the rationale to link wearables data with electronic health records nationwide as a window into behavioral activity choice as a modifiable risk factor for chronic diseases. We may find substantial variation in activity and disease prevalence/severity by socioeconomic status, which would motivate studies/interventions to reduce these health disparities.

Demographic Categories of Interest

  • Race / Ethnicity
  • Geography
  • Access to Care
  • Education Level
  • Income Level

Research Team

Owner:

  • Evan Brittain - Mid-career Tenured Researcher, Vanderbilt University Medical Center
  • Jeffrey Annis - Other, Vanderbilt University Medical Center
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