Nia Nikkhahmanesh

Graduate Trainee, University of Arizona

2 active projects

V5 of Checkpoint Inhibitors

How many patients taking checkpoint inhibitors develop hypothyroidism after initiating therapy? This question will help clinicians understand the likelihood of potential thyroid complications associated with checkpoint inhibitor therapy. In addition, it can guide diagnoses and treatment of patients and result…

Scientific Questions Being Studied

How many patients taking checkpoint inhibitors develop hypothyroidism after initiating therapy?

This question will help clinicians understand the likelihood of potential thyroid complications associated with checkpoint inhibitor therapy. In addition, it can guide diagnoses and treatment of patients and result in more comprehensive patient care.

Project Purpose(s)

  • Disease Focused Research (hypothyroidism)

Scientific Approaches

We plan to use the All of Us research database to stratify patients by treatment with a checkpoint inhibitor and development of hypothyroidism after treatment initiation. We will evaluate data from 2012-2018 and calculate the incidence.

Anticipated Findings

We anticipate finding a higher incidence of hypothyroidism in patients on checkpoint inhibitor pharmacotherapy. These findings will help clinicians identify potential complications of treatment which will allow them to properly address concerns.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Research Team

Owner:

Collaborators:

  • Anand Gandhi - Research Associate, Banner Health
  • Emma Kar - Graduate Trainee, University of Arizona

Checkpoint Inhibitors

How many patients taking checkpoint inhibitors develop hypothyroidism after initiating therapy? This question will help clinicians understand the likelihood of potential thyroid complications associated with checkpoint inhibitor therapy. In addition, it can guide diagnoses and treatment of patients and result…

Scientific Questions Being Studied

How many patients taking checkpoint inhibitors develop hypothyroidism after initiating therapy?

This question will help clinicians understand the likelihood of potential thyroid complications associated with checkpoint inhibitor therapy. In addition, it can guide diagnoses and treatment of patients and result in more comprehensive patient care.

Project Purpose(s)

  • Disease Focused Research (hypothyroidism)

Scientific Approaches

We plan to use the All of Us research database to stratify patients by treatment with a checkpoint inhibitor and development of hypothyroidism after treatment initiation. We will evaluate data from 2012-2018 and calculate the incidence.

Anticipated Findings

We anticipate finding a higher incidence of hypothyroidism in patients on checkpoint inhibitor pharmacotherapy. These findings will help clinicians identify potential complications of treatment which will allow them to properly address concerns.

Demographic Categories of Interest

This study will not center on underrepresented populations.

Research Team

Owner:

Collaborators:

  • Anand Gandhi - Research Associate, Banner Health
  • Emma Kar - Graduate Trainee, University of Arizona
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