Brian Eisinger

Research Fellow, Indiana University

1 active project

NHPI cardiometabolic workspace

We are studying genetic risk for cardiovascular and metabolic disease, focusing on the genetic diversity of Native Hawaiian / Pacific Islander (NHPI) populations, which have been historically underrepresented in research and underserved in healthcare. We seek to understand and address…

Scientific Questions Being Studied

We are studying genetic risk for cardiovascular and metabolic disease, focusing on the genetic diversity of Native Hawaiian / Pacific Islander (NHPI) populations, which have been historically underrepresented in research and underserved in healthcare. We seek to understand and address the unique genetic vulnerabilities faced by these groups to empower precision approaches to drug discovery and healthcare.

Project Purpose(s)

  • Disease Focused Research (Cardiovascular and metabolic disease)

Scientific Approaches

We plan to use genome-wide association studies (GWAS) and regression modeling approaches to characterize disease prevalence and genetic risk architecture in NHPI people compared to other groups.

Anticipated Findings

We anticipate discovering that there is indeed a unique genetic basis for cardiometabolic disease risk in NHPI people, or the alternative that genetic risk is largely unchanged and disparities in health outcomes can be attributed to social determinants of health, which would warrant its own investigation.

Demographic Categories of Interest

  • Race / Ethnicity

Data Set Used

Controlled Tier

Research Team

Owner:

Collaborators:

  • Xiuan Guo - Undergraduate Student, University of Chicago
  • Seongyeon Yang - Graduate Trainee, University of Chicago
  • Kai Walsh - Undergraduate Student, University of Chicago
  • George Lord - Undergraduate Student, University of Chicago
  • Tigran Bdoyan - Undergraduate Student, University of Chicago
  • Ravindra Mangar - Undergraduate Student, University of Chicago
1 - 1 of 1
<
>
Request a Review of this Research Project

You can request that the All of Us Resource Access Board (RAB) review a research purpose description if you have concerns that this research project may stigmatize All of Us participants or violate the Data User Code of Conduct in some other way. To request a review, you must fill in a form, which you can access by selecting ‘request a review’ below.