Research Associate, Hebrew SeniorLife
1 active project
Drug repurposing for osteoarthritis
Scientific Questions Being Studied
There is a great need for new drug development for osteoarthritis (OA). Some drugs and biologics already in use to treat other conditions may be effective for OA. Identifying which of these already approved drugs may have effects on OA can help reduce the cost and time needed for development of new OA therapies. Our study aims to identify one or more promising treatments for OA by assessing whether certain drug classes may have effects on OA in a large, diverse dataset.
- Disease Focused Research (osteoarthritis)
We plan to use drug epidemiology approaches to determine whether certain drug classes affect OA. When genetic data are available, we will use Mendelian randomization approaches to determine whether variation in genes that mimic the effects of these drug classes are associated with OA.
Our study will provide insights into new drug classes that may be repurposed for OA. We anticipate that our findings will help accelerate drug development for OA by identifying promising new drug targets that can be used for future development of OA therapeutics.
Demographic Categories of Interest
This study will not center on underrepresented populations.
- Michelle Yau - Research Associate, Hebrew SeniorLife
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